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| Synonym: | PD-125,944, N6-[2-(3,5-Dimethoxyphenyl)-2-(2-methylphenyl)-ethyl]adenosine |
| CAS Number: | 120442-40-2 |
| Linear Formula: | C27H31N5O6 |
| Molecular Weight: | 521.56 |
| MDL number: | MFCD00069262 |
Description
| Biochem/physiol Actions | Selective A2 adenosine receptor agonist. |
| Legal Information | Manufactured and sold with the permission of Parke-Davis. |
Properties
| form | solid |
| color | white |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.67 mg/mL |
| | DMSO: 100 mg/mL |
| | methanol: 3 mg/mL |
| | 0.1 M NaOH: insoluble |
| | H2O: insoluble |
Safety
References
| reference | Bridges, N6-[2-(3,5-Dimethoxyphenyl)-2-(2-methylphenyl)-ethyl]adenosine and its uronamide derivatives. Novel adenosine agonists with both high affinity and high selectivity for the adenosine A2 receptor. J. Med. Chem. 31, 1282, (1988) Abstract |
| | Okada, M., Adenosine A1 and A2 receptors modulate extracellular dopamine levels in rat striatum. Neurosci. Lett. 212, 53, (1996) Abstract |
